Carbapenemase
Product name
HWTS-OT085E/F/G/H -Carbapenemase Detection Kit (Colloidal Gold)
Epidemiology
Carbapenem antibiotics are atypical β-lactam antibiotics with the broadest antibacterial spectrum and strongest antibacterial activity[1]. Because of its stability to β-lactamase and low toxicity, it has become one of the most important antibacterial drugs for the treatment of severe bacterial infections. Carbapenems are highly stable to plasmid-mediated extended-spectrum β-lactamases (ESBLs), chromosomes and plasmid-mediated cephalosporinases (AmpC enzymes)[2].
Technical Parameters
| Target region | NDM, KPC, OXA-48, IMP and VIM carbapenemases |
| Storage temperature | 4℃-30℃ |
| Sample type | Bacterial samples obtained after culture |
| Shelf life | 24 months |
| Auxiliary instruments | Not required |
| Extra Consumables | Not required |
| Detection time | Bacterial samples obtained after culture |
| LoD |
NDM type: 0.15ng/mL KPC type: 0.4ng/mL OXA-48 type : 0.1ng/mL IMP type :0.2ng/mL VIM type :0.3ng/mL. |
| Hook effect | For NDM, KPC, OXA-48 type carbapenemase, no hook effect is found in the range of 100ng/mL; for IMP, VIM type carbapenemase, no hook effect is found in the range of 1μg/mL. |
Work Flow
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