Monkeypox Virus Nucleic Acid

Monkeypox (MPX) is an acute zoonotic infectious disease caused by Monkeypox Virus (MPXV). MPXV is round-bricked or oval in shape, and is a double-stranded DNA virus with a length of about 197Kb. The disease is mainly transmitted by animals, and humans could become infected by being bitten by infected animals or by direct contact with the blood, body fluids and rash of infected animals. The virus can also be transmitted between people, primarily through respiratory droplets during prolonged, direct face-to-face contact or through direct contact with a patient's body fluids or contaminated objects. The clinical symptoms of monkeypox infection in humans are similar to those of smallpox, generally after a 12-day incubation period, appearing fever, headache, muscle and back pain, enlarged lymph nodes, fatigue and discomfort. The rash appears after 1-3 days of the fever, usually first on the face, but also in other parts. The disease course generally lasts 2-4 weeks, and the mortality rate is 1%-10%. Lymphadenopathy is one of the main differences between this disease and smallpox.

The test results of this kit should not be used as the sole indicator for the diagnosis of monkeypox virus infection in patients, which must be combined with the clinical characteristics of the patient and other laboratory test data to correctly determine the infection of the pathogen, and formulate a reasonable treatment plan to make the treatment safe and effective.