News - [World Cancer Day] We have the greatest wealth-health.

The concept of tumor

Tumor is a new organism formed by abnormal proliferation of cells in the body, which often manifests as abnormal tissue mass (lump) in the local part of the body. Tumor formation is the result of serious disorder of cell growth regulation under the action of various tumorigenic factors. Abnormal proliferation of cells leading to tumor formation is called neoplastic proliferation.

In 2019, Cancer Cell published an article recently. Researchers found that metformin can significantly inhibit tumor growth in fasting state, and suggested that PP2A-GSK3β-MCL-1 pathway may be a new target for tumor treatment.

The main difference between benign tumor and malignant tumor

Benign tumor: slow growth, capsule, swelling growth, sliding to the touch, clear boundary, no metastasis, generally good prognosis, local compression symptoms, generally no whole body, usually does not cause death of patients.

Malignant tumor (cancer): rapid growth, invasive growth, adhesion to surrounding tissues, inability to move when touched, unclear boundary, easy metastasis, easy recurrence after treatment, low fever, poor appetite in the early stage, weight loss, severe emaciation, anemia and fever in the late stage, etc. If not treated in time, it often leads to death.

"Because benign tumors and malignant tumors not only have different clinical manifestations, but more importantly, their prognosis is different, so once you find a lump in your body and the above symptoms, you should seek medical advice in time."

Individualized treatment of tumor

Human Genome Project and International Cancer Genome Project

The Human Genome Project, which was officially launched in the United States in 1990, aims to unlock all the codes of about 100,000 genes in the human body and draw the spectrum of human genes.

In 2006, the International Cancer Genome Project, jointly launched by many countries, is another major scientific research after the Human Genome Project.

Core problems in tumor treatment

Individualized diagnosis and treatment = Individualized diagnosis+targeted drugs

For most different patients suffering from the same disease, the treatment method is to use the same medicine and standard dosage, but in fact, different patients have great differences in treatment effect and adverse reactions, and sometimes this difference is even fatal.

Targeted drug therapy has the characteristics of highly selective killing of tumor cells without killing or only rarely damaging normal cells, with relatively small side effects, which effectively improves the quality of life and therapeutic effect of patients.

Because targeted therapy is designed to attack specific target molecules, it is necessary to detect tumor genes and detect whether patients have corresponding targets before taking drugs, so as to exert its curative effect.

Tumor gene detection

Tumor gene detection is a method to analyze and sequence the DNA/RNA of tumor cells.

The significance of tumor gene detection is to guide the drug selection of drug therapy (targeted drugs, immune checkpoint inhibitors and other new AIDS, late treatment), and to predict the prognosis and recurrence.

Solutions provided by Acer Macro & Micro-Test

Human EGFR Gene 29 Mutations Detection Kit (Fluorescence PCR）

Used for qualitative detection of common mutations in exon 18-21 of EGFR gene in human non-small cell lung cancer patients in vitro.

1. The introduction of internal reference quality control in the system can comprehensively monitor the experimental process and ensure the experimental quality.

2. High sensitivity: the mutation rate of 1% can be detected stably in the background of 3ng/μL wild-type nucleic acid reaction solution.